While on a fishing trip, Harry Baldwin (Ray Milland) and his family hear an explosion and realize that Los Angeles has been leveled by a nuclear attack. Looters and killers are everywhere. Escaping to the hills with his family, he sets about the business of surviving in a world where, he knows, the old ideals of humanity will be first casualties. Not one to give up, he holds up a store for supplies and hides the family in a cave.

Southland Tales is an ensemble piece set in the futuristic landscape of Los Angeles on July 4, 2008, as it stands on the brink of social, economic and environmental disaster. Boxer Santaros is an action star who's stricken with amnesia. His life intertwines with Krysta Now, an adult film star developing her own reality television project, and Ronald Taverner, a Hermosa Beach police officer who holds the key to a vast conspiracy.